“How does the living organism avoid decay? … It feeds on negative entropy.”
— Erwin Schrödinger, What is Life? (1944)
More than eighty years ago, Schrödinger proposed that life sustains itself by staying far from thermodynamic equilibrium, continuously consuming energy to build order out of disorder. In his view, living matter avoids decay by drawing on energy gradients — by “feeding on negative entropy.”
Schrödinger’s insight that life sustains itself by remaining far from equilibrium continues to inspire modern science. Today, this philosophy underpins the rapidly growing field of non-equilibrium soft and active matter, where chemical energy is harnessed to create smart materials that move, assemble, and communicate much like living cells.